Category: Library

May 7, 2018
PTSD & BHRT - A Fresh New APproach

It’s not news to anyone in the military community that many of our honorable veterans return from active service suffering, often in silence, from Post-Traumatic Stress Disorder or “PTSD.” Standard clinical protocol in V.A. hospitals across the nation for treating PTSD include long-term prescriptions of Selective Serotonin Reuptake Inhibitors (SSRIs) or Serotonin & Norepinephrine Reuptake Inhibitors (SNRIs). Prozac, Paxil, Zoloft, and Effexor are examples of the most commonly prescribed anti-depressants for PTSD and related conditions such as depression and Traumatic Brain Injury (TBI). Some doctors may also prescribe other types of anti-depressants, Monoamine Oxidase Inhibitors, Antipsychotics, Beta-blockers, or Benzodiazepines if SSRIs and SNRIs prove ineffective.[i]

The central issue with all these medications is that they do not fundamentally address the root of the problem. They rarely resolve the disorder, but rather, “numb” the individual by temporarily masking his/her symptoms. All of these drugs come with a laundry list of unpleasant and/or dangerous side effects including drowsiness, anxiety, insomnia, nausea, dry mouth, dizziness, diarrhea, vision problems, headaches, heart palpitations, erectile dysfunction and suicidal thoughts. [ii]

Post-Traumatic Stress Disorder is a serious and devastating condition resulting from emotional and/or physical trauma. About 30% of soldiers who have served in war zones are later diagnosed with PTSD.[iii] The treatment for their suffering, which can last for years, is typically limited to counseling and use of prescription drugs. Symptoms of PTSD include difficulty sleeping, nightmares, flashbacks, mental exhaustion, and significant emotional distress anytime the victim is reminded of the traumatic event(s).[iv] The Department of Veterans Affairs reports that 20 American military veterans per day commit suicide because of PTSD.[v]

Moreover, PTSD is not limited to the military population. In fact, it is estimated that 5.2 million people in the United States are currently suffering with this debilitating condition.[vi]

PTSD and BHRT – New Solutions

Fortunately, a new and effective alternative method of treatment is available. Rather than masking the problem with drugs, some PTSD patients have discovered something that works better than anti-depressants; specifically, bio-identical hormone replacement therapy, which is infinitely safer, in addition to being more effective.

And here is why. The brain controls the production of hormones, and many of the symptoms of PTSD are amplified by low testosterone.[vii] Chronic anxiety and depression have been proven to lower natural hormone levels,[viii] and low levels of hormones can trigger more anxiety and depression.[ix] These two conditions, sadly, worsen over time in a negative feedback loop.

Simply balancing a person’s testosterone, estrogen and progesterone back to normal levels can reduce or eliminate the symptoms of PTSD, allowing him or her to return to a healthy, vibrant life. It is a safe, proven and effective solution.

BHRT – All-natural solutions

Unlike synthetic hormones, bio-identical hormones are created from vegetables or plants, such as yams or soy. They are formulated to replace your natural hormones exactly, with an identical chemical structure. In fact, the body cannot distinguish them from the biological hormones it already produces. Because of their purity, bio-identical hormones do not cause the same unpleasant and dangerous side effects as synthetic hormones.[x]

In addition to the reduction or elimination of the symptoms of PTSD, patients on bio-identical hormone replacement therapy experience improved strength, higher bone density, development of lean muscle mass, lower cholesterol levels, deeper sleep, greater concentration, higher levels of energy, a heightened interest in sex, and an overall sense of well-being.[xi]

Pellets Provide Gradual Hormone Release

Bio-identical hormones are administered in the form of tiny, subcutaneous pellets that are inserted underneath the skin, using an anesthetic, every three to four months. The BHRT pellets are placed in the upper part of the buttocks and slowly dissolve over time, which mimics the gradual secretion of the body’s natural hormones.

Dr. Gregory Brannon Provides Solutions

Dr Greg Brannon - Medical Director, The Youth Institute BHRTAs a medical doctor and an expert in anti-aging medicine, I have helped thousands of men and women regain their health and happiness through the use of bio-identical hormone replacement therapy. For the past 7 years, my team and I have been doing pellet therapy in my North Carolina BHRT offices, and the results have been phenomenal. I have had the pleasure of advising military men and women, many of whom have become my patients. It is a joy and a privilege for me to be able to restore the strength, vitality, and emotional and physical well-being of those who have made the sacrifice of serving in our armed forces.

If you would like to learn more about bio-identical hormone replacement therapy for the treatment of PTSD, depression, TBI, or other adverse health conditions, please visit our website at:

https://www.youthinstitutebhrt.com/

I look forward to scheduling a consultation with you and answering any questions you may have one-on-one.

Dr. Gregory Brannon, M.D.


Links to References:

[i] https://www.webmd.com/mental-health/what-are-treatments-for-posttraumatic-stress-disorder#3

[ii] https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825

[iii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297500/

[iv] https://www.ptsd.va.gov/public/ptsd-overview/basics/symptoms_of_ptsd.asp

[v] https://www.wsj.com/articles/u-s-veterans-commit-suicide-at-rate-of-20-a-day-va-says-1467908311

[vi] http://www.ptsd.ne.gov/what-is-ptsd.html

[vii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520791/

[viii] https://news.utexas.edu/2010/09/27/stress-hormone-blocks-testosterones-effects-study-shows

[ix] https://www.healthline.com/health/low-testosterone/depression

[x] http://www.lifeextension.com/Magazine/2009/10/Bioidentical-Hormones/Page-01

[xi] https://www.youthinstitutebhrt.com/

Posted in BHRT Hormone Treatments, Library by Jack
February 19, 2018

Download the Ketogenic Diet – Dr Greg Brannon MP3

Hello, I’m Dr Greg Brannon, the medical director here at the Youth Institute. Confusion. What do I eat, this diet and that diet, this diet. Let’s clear the confusion up. Previously in American history, and across the world now, they eat more organically and naturally. There is less cardiovascular disease, less diabetes, less obesity. See, it’s important that we understand what nutrition really is. What has happened in the last hundred years, the best health aspects of America have occurred because of hygiene, clean water, soap, washing hands, but the sad part is these diseases of obesity and diabetes and cancer and cardiovascular disease have increased in the last hundred years, while supposedly our medical care has been better. And yes, our medical care is phenomenal for Traumas, and accidents, and these high tech surgeries, but overall, when I get back to the basis of nutrition that keeps our body healthy… See our body is built not just to exist, but to thrive in this environment if given the right supplementation, the right hormone balance, and the right nutrition.

See, we’ve become accustomed to literally these chronic diseases. The question is why? Where’d they come from? Thomas Jefferson said, if a people ever allows the government to tell them what foods to eat and what medicine to take, they’ll be in the worst state of tyranny. Let that sink in. See the government is not the best caretaker of you. The king and queen is in the mirror. That’s you and I. Knowledge is power. We can’t rely on so called experts and simply wait for them to the ivory towers upon high coming down and tell us how to eat. That’s been proven not to be beneficial. I believe in experts. I believe information is critically important, but we should read as much as possible and absorb as much as possible because the responsibility in your health falls upon you.

What’s very interesting is, previously in American history when we had less heart attacks in obesity and diabetes, we didn’t have the government involved in the diet. 1977 was a very interesting time. That’s when the grain companies lobbied to push through the government to have an American Standard Diet based upon government regulations. Let that sink in. Government regulations pushed through by the grain company. The Food Pyramid. When you look back at the data of cardiovascular disease, diabetes, Atherosclerosis, Metabolic Syndrome, pauses to ovarian syndrome, they’ve all increased since the mid seventies when we became a more of a fat and protein society to more of a carbohydrate eating society. That causes the insulin resistance and causes all the complications we have. So let’s back up here and say OK, moving politics, because when government gets involved, their coercive involvement of pushing their, their, their dollars and their, and their power about regulations – that actually skews the free market. Let’s let you and I dictate what we want to eat by using the free market and our own knowledge.

So when I want to do here at the Youth Institute is really very important. This is not a weight clinic. What we look at, very simply, is you as the individual. We know that the foundational base built is crucial on having physiological, levels, uh, levels of biological hormones proper without that proper hormonal balance and nothing really works. They have the right supplementation that this co factors to let the enzymatic processes that our bodies already have to be at their optimal. Then we supply it the right nutrition. That’s what’s crucial. So the American Standard Diet versus what we’ve heard about ketogenic diets, Paleo diets, these other kinds of diets around the world, anything that moves away from a high carbohydrate diet is better. But it looks like the literature we looked at before previously, last 50-100 years is we ate predominantly fat. Healthy fat has been the mainstay of a healthy diet over the last thousands of years.

So we look at America, it’s 50 percent carbohydrate, 35 percent fat and only 15 percent protein, but that has led, as I talked about, living with these chronic aspect of diseases. A ketogenic diet is very important. About 70 percent essential healthy fats, 20 percent of high quality proteins and 10 percent of carbohydrates from non starchy aspects like leaf green leafy vegetables, Broccoli, Brussels sprouts, some low glycemic lentils, the healthy type of carbohydrates. See a ketogenic diet is this – it’s very low in carbohydrates, moderately high in high quality dietary proteins and high in quality high essential fats. The biochemistry is very interesting on this. It’s that the way our body works is our body can use either sugar or fat for energy, and protein as well, but it’s important to save protein for our structural and enzymatic aspects of our life, so essentially between fat and sugar.

Our bodies stores about 36 hours of sugar as glycogen in your muscle and in our liver. After our 36 to 40 hours of no sugar, our body will deplete that sugar and then turn to adipose. What’s important is about a three week span, if you could actually deplete the glycogen, become an adipose burner, a fat burner. We actually now become our body wants it, wants to use that. There’s a couple of reasons for this. Ketones, which is a byproduct of, the ketone in our bodies. The byproduct of fat metabolism and used as an energy source is actually like the the currency of fat energy – is three times more efficient than sugar. It actually helps protect the Mitochondria. It actually is a cleaner energy source, meaning there’s less free radicals, less damage, so it takes less energy to actually utilize sugar, to utilize fat versus sugar as energy. The benefits of this is interesting. At the brain, using ketones, which I get three times more efficient than sugar, the ketone bodies as energy for the brain, it’s been shown to have actually more nerve and synaptic growth with that within the brain, connections themselves, which has a mental alertness, increases improved cognitive ability and mental sharpness.

Blood sugar metabolism, helps fight insulin resistance – our bodies keeping our blood sugar at a constant level, not these peaks, these peaks, peaks and valleys. Also, it’s very interesting – our cardiovascular health is shown that the actually the Mitochondria, and the cardiac tissue actually uses energy better as a fat cells, again, have more efficiency to the heart and fit and vascular system. A byproduct, this is not the goal of this, but a byproduct is to lose weight, but what I’m saying is to be the healthy weight, you’re supposed to be. A little, just weight losing by itself is not the end all be all. As long as it falls together with a natural losing of weight meaning I have a portion of muscle and adipose together. All this is based upon the foundational principle of having the hormones balanced at the optimal physiological level.

You do the right supplementation and that allows you to be the best you can be. One little interesting thing on sugar – Dr Otis Warburg in 1924, actually he won the Nobel Prize in 1931 if I’m correct on that, he actually showed that cancer cells only grow in glycolysis, which is using sugar. It actually cannot grow, in a ketotic state. That’s a very interesting aspect because the cancer cells need sugar and fat is their enemy. See, we don’t get fat. We don’t get unhealthy by eating fats. We get unhealthy by eating too many sugars in a proportion that is not built physiological for our body.

So the sum of this little video up here is this – you are what you eat. Don’t allow ignorance to be our excuse. Let’s attack out there. Google. The research world is out there. Do your research. Do your work. Ask questions. Understand that it’s very important that we age and age gracefully. We have to regain our youthful exuberance for life, but we need a healthy, healthy body to do that. We do that – tomorrow can be better than today. Again, this is Dr Greg Brannon, at The Youth Institute, the medical director. I thank you for your time.

Posted in Library, Wellness by Jack | Tags: , , ,
June 28, 2017

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.

The primary objective was to update the guidelines for the evaluation and treatment of androgen deficiency syndromes in adult men.

Thank you to the Authors for a job well done. Greg Brannon MD.

Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM; Task Force, Endocrine Society.

OBJECTIVE:

Our objective was to update the guidelines for the evaluation and treatment of androgen deficiency syndromes in adult men published previously in 2006.

PARTICIPANTS:

The Task Force was composed of a chair, selected by the Clinical Guidelines Subcommittee of The Endocrine Society, five additional experts, a methodologist, and a medical writer. The Task Force received no corporate funding or remuneration.

CONCLUSIONS:

We recommend making a diagnosis of androgen deficiency only in men with consistent symptoms and signs and unequivocally low serum testosterone levels. We suggest the measurement of morning total testosterone level by a reliable assay as the initial diagnostic test. We recommend confirmation of the diagnosis by repeating the measurement of morning total testosterone and, in some men in whom total testosterone is near the lower limit of normal or in whom SHBG abnormality is suspected by measurement of free or bioavailable testosterone level, using validated assays. We recommend testosterone therapy for men with symptomatic androgen deficiency to induce and maintain secondary sex characteristics and to improve their sexual function, sense of well-being, muscle mass and strength, and bone mineral density. We recommend against starting testosterone therapy in patients with breast or prostate cancer, a palpable prostate nodule or induration or prostate-specific antigen greater than 4 ng/ml or greater than 3 ng/ml in men at high risk for prostate cancer such as African-Americans or men with first-degree relatives with prostate cancer without further urological evaluation, hematocrit greater than 50{11ec5d4ffb95386a7ead9a4c5941bf1aadd378ea750d3f5f48948cd3f1f66c72}, untreated severe obstructive sleep apnea, severe lower urinary tract symptoms with International Prostate Symptom Score above 19, or uncontrolled or poorly controlled heart failure. When testosterone therapy is instituted, we suggest aiming at achieving testosterone levels during treatment in the mid-normal range with any of the approved formulations, chosen on the basis of the patient’s preference, consideration of pharmacokinetics, treatment burden, and cost. Men receiving testosterone therapy should be monitored using a standardized plan.

To view the complete study, click on the link below.

https://www.ncbi.nlm.nih.gov/pubmed/20525905

Posted in Library by Jack | Tags:
June 28, 2017

 

This study investigates why Sex steroid levels are related to metabolic outcomes that could convey higher risk of premature death.  Araujo AB, Kupelian V, Page ST, Handelsman DJ, Bremner WJ, McKinlay JB.

BACKGROUND:

Sex steroid levels are related to metabolic outcomes that could convey higher risk of premature death.

METHODS:

We examined whether total or free testosterone, dihydrotestosterone, and sex hormone-binding globulin levels are related to all-cause or cause-specific mortality in men. Data were obtained from the Massachusetts Male Aging Study, a population-based cohort study of 1709 men aged 40 to 70 years. Men were followed up for all-cause and cause-specific mortality.

RESULTS:

Complete data were available for 1686 men, with 395 deaths occurring during 15.3 years of follow-up. With age adjustment, dihydrotestosterone and sex hormone-binding globulin levels were associated with ischemic heart disease mortality, and free testosterone level was associated with respiratory mortality. In multivariate-adjusted models, higher free testosterone (P=.02) and lower dihydrotestosterone (P=.04) levels were significantly associated with ischemic heart disease mortality, although the latter association was not robust to differences in model selection. The relative risk of death from ischemic heart disease per 1-SD lower free testosterone level was 0.80 (95{11ec5d4ffb95386a7ead9a4c5941bf1aadd378ea750d3f5f48948cd3f1f66c72} confidence interval, 0.64-0.99). Free testosterone level was significantly associated with respiratory mortality (P=.002), with a multivariate-adjusted relative risk per 1-SD lower free testosterone level of 1.90 (95{11ec5d4ffb95386a7ead9a4c5941bf1aadd378ea750d3f5f48948cd3f1f66c72} confidence interval, 1.24-2.92). Total testosterone level was unrelated to mortality, and sex hormone-binding globulin was not significantly associated with mortality after multivariate adjustment.

CONCLUSIONS:

In men, endogenous sex steroid levels seem to have relatively weak associations with mortality. These data provide little support for the hypothesis that endogenous sex steroid levels are associated with risk of premature death but suggest that further investigation of the relationship between sex steroids and mortality from ischemic heart disease and respiratory disease may be warranted.

For more information, click on the link below.

https://www.ncbi.nlm.nih.gov/pubmed/?term=Araujo+AB.+Sex+steroids+and+all+cause+specific+mortality+in+men

Posted in Library by Jack | Tags:
June 28, 2017

 

This is a great study carried out by Dr’s  Agarwal PK & Oefelein MG. that states “prostate cancer has been an absolute contraindication for testosterone supplementation.”

Greg Brannon, M.D.

PURPOSE:

A history of prostate cancer has been an absolute contraindication for testosterone supplementation. We studied a cohort of hypogonadal patients treated with radical retropubic prostatectomy (RRP) for organ confined prostate cancer to determine if testosterone replacement therapy (TRT) could be efficacious and administered safely without causing recurrent prostate tumor.

MATERIALS AND METHODS:

Ten hypogonadal patients previously treated with RRP for organ confined prostate cancer were identified. They presented with low serum total testosterone (TT) and symptoms of hypogonadism after RRP. Patients had baseline serum determinations of prostate specific antigen (PSA) and TT, and were started on testosterone supplementation. They were assessed periodically for changes in PSA and TT, and for symptomatic improvement using the hormone domain of the Extended Prostate Inventory Composite Health Related Quality of Life questionnaire.

RESULTS:

At a median followup of 19 months no patient had detectable (greater than 0.1 ng/ml) PSA. TT increased significantly after starting TRT from a mean +/- SD of 197 +/- 67 to 591 +/- 180 ng/dl (p = 0.0002). The Hormone Domain of the Extended Prostate Inventory Composite Health Related Quality of Life questionnaire increased significantly from 38 +/- 5 to 49 +/- 3 (p = 0.00005), primarily due to a decrease in hot flashes and an increase in energy level.

CONCLUSIONS:

At a median of 19 months of TRT hypogonadal patients with a history of prostate cancer had no PSA recurrence and had statistically significant improvements in TT and hypogonadal symptoms. In highly select patients after RRP TRT can be administered carefully and with benefit to hypogonadal patients with prostate cancer.

To visit the full report, click on the link below.

https://www.ncbi.nlm.nih.gov/pubmed/15643240

 

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